Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (SR2013)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22385

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22385-100ul
NBP3-22385-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2013

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Activin RIA/ALK-2 Antibodies »

Product Summary for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (SR2013)

Immunogen

A synthesized peptide derived from human Activin RIA/ALK-2/Activin Receptor Type 1 (Uniprot #: Q04771)

Specificity

Detects endogenous levels of total Activin RIA/ALK-2/Activin Receptor Type 1

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

57 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (SR2013)

Western Blot: Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (SR2013) [NBP3-22385] -

Western Blot: Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (SR2013) [NBP3-22385] - Western blot analysis using NBP3-22385 in Human fetal heart lysate.

Applications for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (SR2013)

Application
Recommended Usage

Immunoprecipitation

1:50

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Activin RIA/ALK-2

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.

Long Name

Activin Receptor IA

Alternate Names

ActivinRIA, ACVR1, ALK-2, ALK2

Gene Symbol

ACVR1

Additional Activin RIA/ALK-2 Products

Product Documents for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (SR2013)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Activin RIA/ALK-2/Activin Receptor Type 1 Antibody (SR2013)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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