Activin RIIB Antibody (S01-2I1)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19830

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-19830-100ul
NBP3-19830-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S01-2I1

Concentration

0.3 mg/ml

View all Activin RIIB Antibodies »

Product Summary for Activin RIIB Antibody (S01-2I1)

Immunogen

A synthetic peptide of human Activin RIIB (Uniprot # Q13705)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

58 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Activin RIIB Antibody (S01-2I1)

Western Blot: Activin RIIB Antibody (S01-2I1) [NBP3-19830]

Western Blot: Activin RIIB Antibody (S01-2I1) [NBP3-19830]

Western Blot: Activin RIIB Antibody (S01-2I1) [NBP3-19830] - Western blot detection of Activin RIIB in CHO-K1, mouse Brain using NBP3-19830 (1:1000 diluted)

Applications for Activin RIIB Antibody (S01-2I1)

Application
Recommended Usage

Western Blot

1/1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Activin RIIB

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. [provided by RefSeq]

Long Name

Activin Receptor IIB

Alternate Names

ActivinRIIB, ACVR2B

Gene Symbol

ACVR2B

Additional Activin RIIB Products

Product Documents for Activin RIIB Antibody (S01-2I1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Activin RIIB Antibody (S01-2I1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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