ACTL7A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-15270

Novus Biologicals, part of Bio-Techne
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NBP2-15270
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (92%), Mouse (91%), Primate (98%), Rat (92%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ACTL7A Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human ACTL7A. The exact sequence is proprietary.

Reactivity Notes

Chimpanzee (98%).

Localization

Cytoplasm; cytoskeleton

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

49 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ACTL7A Antibody

Western Blot: ACTL7A Antibody [NBP2-15270]

Western Blot: ACTL7A Antibody [NBP2-15270]

Western Blot: ACTL7A Antibody [NBP2-15270] - Sample (30 ug of whole cell lysate) A: U87-MG 10% SDS PAGE; antibody diluted at 1:1000.

Applications for ACTL7A Antibody

Application
Recommended Usage

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: ACTL7A

The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known. [provided by RefSeq]

Alternate Names

actin-like 7A, actin-like 7-alpha, actin-like protein 7A, actin-like-7-alpha

Gene Symbol

ACTL7A

UniProt

Q9Y615 (Human)

Additional ACTL7A Products

Product Documents for ACTL7A Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ACTL7A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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