ADAMTSL5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-93438

Novus Biologicals, part of Bio-Techne
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NBP1-93438
NBP1-93438-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ADAMTSL5 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: AHRLLHYCGSDFVFQARVLGHHHQAQETRYEVRIQLVYKNRSPLRAREYVWAPGHCPCPMLAPHRDYLMAVQRLVSPDGTQDQ

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (83%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ADAMTSL5 Antibody

Western Blot: ADAMTSL5 Antibody [NBP1-93438]

Western Blot: ADAMTSL5 Antibody [NBP1-93438]

Western Blot: ADAMTSL5 Antibody [NBP1-93438] - Analysis in human cell line CACO-2.
Immunocytochemistry/ Immunofluorescence: ADAMTSL5 Antibody [NBP1-93438]

Immunocytochemistry/ Immunofluorescence: ADAMTSL5 Antibody [NBP1-93438]

Immunocytochemistry/Immunofluorescence: ADAMTSL5 Antibody [NBP1-93438] - ADAMTSL5 distribution and co-localization with melanocytes. Representative double immunofluorescence images of ADAMTSL5 made in rabbit (A), in psoriasis lesional skin confirming expression of ADAMTSL5 in keratinocytes and co-localization of ADAMTSL5 with melanocytes (Melan-A). Cells that co-express the two markers in a similar location are yellow in color. White line denotes the junction between epidermis and the dermis. Size bar = 100um. Image collected and cropped by CiteAb from the following publication (hilarispublisher.com/open-access/cutaneous-expression-of-a-disintegrinlike-and-metalloprotease-domaincontaining-thrombospondin-type-1-motiflike-5-adamtsl5-in-psori-2376-0427-1000244.pdf), licensed under a CC-BY license.
Immunocytochemistry/ Immunofluorescence: ADAMTSL5 Antibody [NBP1-93438]

Immunocytochemistry/ Immunofluorescence: ADAMTSL5 Antibody [NBP1-93438]

Immunocytochemistry/Immunofluorescence: ADAMTSL5 Antibody [NBP1-93438] - Staining of human cell line BJ shows localization to the Golgi apparatus. Antibody staining is shown in green.
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Applications for ADAMTSL5 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

Reactivity reported in (PMID:27857980)

Western Blot

0.04-0.4 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ADAMTSL5

Members of the ADAMTS family contain pro, catalytic, disintegrin-like, cysteine-rich, spacer and a variable number of TS type 1 motifs. In contrast to membrane-anchored ADAMs, ADAMTSs are secreted and are all active proteases. They are essential for aggrecan turnover and procollagen processing, regulation of which is important in many physiological and pathological processes such as angiogenesis and arthritis.

Long Name

ADAMTS-like 5

Alternate Names

ADAMTSL-5, THSD6

Entrez Gene IDs

339366 (Human)

Gene Symbol

ADAMTSL5

UniProt

Q6ZMM2 (Human)

Additional ADAMTSL5 Products

Product Documents for ADAMTSL5 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ADAMTSL5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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