ADCY4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-12214

Novus Biologicals, part of Bio-Techne
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NBP3-12214
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Adenylate Cyclase 4 Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on rat Particulate Adenylyl Cyclase 4 protein.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for ADCY4 Antibody

Western Blot: ADCY4 Antibody [NBP3-12214]

Western Blot: ADCY4 Antibody [NBP3-12214]

Western Blot: ADCY4 Antibody [NBP3-12214] - 1:500 antibody dilution in diluobuffer.
Immunohistochemistry-Paraffin: ADCY4 Antibody [NBP3-12214]

Immunohistochemistry-Paraffin: ADCY4 Antibody [NBP3-12214]

Immunohistochemistry-Paraffin: ADCY4 Antibody [NBP3-12214] - 1:50 dilution in IHC Blocking buffer. DAB (brown) staining and hematoxylin QS (blue) counterstain. 40X magnification. FFPE section.
Immunohistochemistry-Paraffin: ADCY4 Antibody [NBP3-12214]

Immunohistochemistry-Paraffin: ADCY4 Antibody [NBP3-12214]

Immunohistochemistry-Paraffin: ADCY4 Antibody [NBP3-12214] - 1:50 dilution in IHC Blocking buffer. DAB (brown) staining and hematoxylin QS (blue) counterstain. 40X magnification. FFPE section.

Applications for ADCY4 Antibody

Application
Recommended Usage

ELISA

1:10000

Immunocytochemistry/ Immunofluorescence

1:100-1:200

Immunohistochemistry

1:100-1:200

Western Blot

1:500

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary).

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.

Background: Adenylate Cyclase 4

Adenylyl cyclases function to convert ATP to cyclic AMP in response to activation by a variety of hormones, neurotransmitters and other regulatory molecules. Cyclic AMP, in turn, activates several other target molecules to control a broad range of diverse phenomena such as metabolism, gene transcription and memory. Adenylyl cyclases respond to receptor-initiated signals, mediated by the Gs and Gi heterotrimeric G proteins. The binding of an agonist to a Gs-coupled receptor catalyzes the exchange of GDP (bound to Galpha s) for GTP, the dissociation of GTP-Galpha s from Gbetagamma and Galpha s-mediated activation of adenylyl cyclase. Adenylyl cyclase IV (AC IV) and IX mRNA are expressed in all kidney nephron segments. AC IV exhibits moderate staining in type II and type IV fibrocytes in rat cochlea and immunoreactivity is also observed in type I fibrocytes. Activation of the D2 dopaminergic and m4 muscarine receptors inhibits the activity of adenylyl cyclase isozymes I, V, VI and VIII, whereas type II, IV and VII are stimulated and type III is not affected.

Long Name

Adenylate cyclase type 4

Alternate Names

ADCY4, Adenylyl cyclase 4

Gene Symbol

ADCY4

Additional Adenylate Cyclase 4 Products

Product Documents for ADCY4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ADCY4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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