Adenylate Cyclase 3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-60792

Novus Biologicals, part of Bio-Techne
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NBP2-60792
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Adenylate Cyclase 3 Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH. Accession # P21932

Specificity

Specific for endogenous levels of the ~160 kDa adenylate cyclase 3 protein.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

160 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Adenylate Cyclase 3 Antibody

Western Blot: Adenylate Cyclase 3 Antibody [NBP2-60792]

Western Blot: Adenylate Cyclase 3 Antibody [NBP2-60792]

Western Blot: Adenylate Cyclase 3 Antibody [NBP2-60792] - Western blot of rat cortical lysate showing specificimmunolabeling of the ~160 kDa adenylate cyclase III protein.
Immunocytochemistry/ Immunofluorescence: Adenylate Cyclase 3 Antibody [NBP2-60792]

Immunocytochemistry/ Immunofluorescence: Adenylate Cyclase 3 Antibody [NBP2-60792]

Immunocytochemistry/Immunofluorescence: Adenylate Cyclase 3 Antibody [NBP2-60792] - Immunofluorescence of a section of rat hippocampus selectively labeling the neuronal cilia with anti-adenylate cyclase III (1:10,000, red), labeling nuclei with anti-MECP2 (1:1000,green), and Hoechst staining of nuclear DNA.
Immunocytochemistry/ Immunofluorescence: Adenylate Cyclase 3 Antibody [NBP2-60792]

Immunocytochemistry/ Immunofluorescence: Adenylate Cyclase 3 Antibody [NBP2-60792]

Immunocytochemistry/Immunofluorescence: Adenylate Cyclase 3 Antibody [NBP2-60792] - Immunofluorescence of cultured rat neurons and glia showingstrong staining of neuronal cilia using our anti-adenylatecyclase III antibody (red) and axonal and dendritic staining ofalpha II spectrin (green) revealing thesubmembraneous cytoskeleton and DNA (blue).

Applications for Adenylate Cyclase 3 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Western Blot

1:100-1:2000
Application Notes
WB analysis shows bands at 160, 200 kDa

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS with 50% glycerol

Preservative

0.035% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Adenylate Cyclase 3

ADCY3, also known as Adenylate cyclase type 3, is a 129 kDa 1,144 amino acid protein, and is involved in the formation of the secondary messenger protein, cAMP. This protein has also been shown to have interactions with STOML3, CAMK2G, PDE1A, PDE1C, and PDE2A in the Signaling by FGFR, PKA activation in glucagon signaling, DAG and IP3 signaling, Regulation of Water Balance by Renal Aquaporins, and Opioid Signalling pathway. Disease research is currently being studied with relation to ADCY3 and cholera, alcoholism, tuberculosis, and breast cancer.

Long Name

Adenylate cyclase type 3

Alternate Names

AC-III, AC3, ADCY3, Adenylyl cyclase 3, KIAA0511

Gene Symbol

ADCY3

Additional Adenylate Cyclase 3 Products

Product Documents for Adenylate Cyclase 3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Adenylate Cyclase 3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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