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AG-2/AGR2 Antibody (1C3)

Novus Biologicals, part of Bio-Techne | Catalog # H00010551-M03

Novus Biologicals, part of Bio-Techne
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H00010551-M03

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 1C3

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

AGR2 (AAH15503.1, 1 a.a. ~ 175 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MEKIPVSAFLLLVALSYTLARDTTVKPGAKKDTKDSRPKLPQTLSRGWGDQLIWTQTYEEALYKSKTSNKPLMIIHHLDECPHSQALKKVFAENKEIQKLAEQFVLLNLVYETTDKHLSPDGQYVPRIMFVDPSLTVRADITGRYSNRLYAYEPADTALLLDNMKKALKLLKTEL

Specificity

AGR2 - anterior gradient 2 homolog (Xenopus laevis)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Scientific Data Images for AG-2/AGR2 Antibody (1C3)

Western Blot: AG-2/AGR2 Antibody (1C3) [H00010551-M03]

Western Blot: AG-2/AGR2 Antibody (1C3) [H00010551-M03]

Western Blot: AG-2 Antibody (1C3) [H00010551-M03] - Analysis of AGR2 expression in MCF-7 (Cat # L046V1).
Western Blot: AG-2/AGR2 Antibody (1C3) [H00010551-M03]

Western Blot: AG-2/AGR2 Antibody (1C3) [H00010551-M03]

Western Blot: AG-2 Antibody (1C3) [H00010551-M03] - Analysis of AGR2 expression in transfected 293T cell line by AGR2 monoclonal antibody (M03), clone 1C3. Lane 1: AGR2 transfected lysatE (20 KDa). Lane 2: Non-transfected lysate.
ELISA: AG-2/AGR2 Antibody (1C3) [H00010551-M03]

ELISA: AG-2/AGR2 Antibody (1C3) [H00010551-M03]

ELISA: AG-2 Antibody (1C3) [H00010551-M03] - Detection limit for recombinant GST tagged AGR2 is approximately 0.03ng/ml as a capture antibody.

Applications for AG-2/AGR2 Antibody (1C3)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against cell lysate, transfected lysate and recombinant protein for western blot. It has also been used for ELISA.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: AG-2/AGR2

Anterior gradient homolog 2 (AGR2) is a proto-oncogene that may play a role in cell migration, cell differentiation and cell growth. AGR2 is expressed in a number of different tumor types and high levels of AGR2 correlate with downregulation of the p53 response. AGR2 is being investigated for its use as a potential diagnostic and therapeutic target in various cancers, and AGR2 antibodies are important tools for cancer research.

Long Name

Anterior Gradient 2 Homolog

Alternate Names

AG2, AGR2, GOB-4, HPC8, PDIA17

Entrez Gene IDs

10551 (Human)

Gene Symbol

AGR2

OMIM

606358 (Human)

Additional AG-2/AGR2 Products

Product Documents for AG-2/AGR2 Antibody (1C3)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for AG-2/AGR2 Antibody (1C3)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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