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AG-3/AGR3 Antibody (AGR3.4)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-62196

Novus Biologicals, part of Bio-Techne
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NBP2-62196

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # AGR3.4

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for AG-3/AGR3 Antibody (AGR3.4)

Immunogen

Purified human AGR3 protein

Specificity

The antibody DA-7 reacts with Cytokeratin 18 (45 kDa). Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

20 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for AG-3/AGR3 Antibody (AGR3.4)

Western Blot: AG-3/AGR3 Antibody (AGR3.4) [NBP2-62196]

Western Blot: AG-3/AGR3 Antibody (AGR3.4) [NBP2-62196]

Western Blot: AG-3/AGR3 Antibody (AGR3.4) [NBP2-62196] - Analysis of AGR3 protein by AGR3.1 and AGR3.2 antibody, and of AGR3 and AGR2 protein by AGR3.4 antibody in T47D breast cancer cell line compared to H1229 lung carcinoma cell line.

Applications for AG-3/AGR3 Antibody (AGR3.4)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1 ug/ml

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

1 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS and 0.2% (w/v) high grade BSA (protease free)

Preservative

0.9% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: AG-3

AGR3 is a gene that encodes Anterior Gradient Homolog 3, a protein associated with breast cancer. Also known as Breat Cancer Membrane Protein 11, AG3 has a positive correlation with the expression of estrogen receptor. Its expression is negatively correlated with the expression of the EGF receptor. Because it is expressed in nearly three-quarters of breast cancer cells, it has high potential as a target for breast cancer therapy.

Long Name

Anterior Gradient 3 Homolog

Alternate Names

AG3, AGR3, BCMP11, PDIA18

Gene Symbol

AGR3

Additional AG-3 Products

Product Documents for AG-3/AGR3 Antibody (AGR3.4)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for AG-3/AGR3 Antibody (AGR3.4)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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