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AG-3/AGR3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-15307

Novus Biologicals, part of Bio-Techne
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NBP2-15307

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for AG-3/AGR3 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human AG-3/AGR3. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Chicken (86%).

Localization

Secreted

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

19 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for AG-3/AGR3 Antibody

Western Blot: AG-3/AGR3 Antibody [NBP2-15307]

Western Blot: AG-3/AGR3 Antibody [NBP2-15307]

Western Blot: AG-3/AGR3 Antibody [NBP2-15307] - Sample (30 ug of whole cell lysate) A: A549 B: MCF-7 12% SDS PAGE; antibody diluted at 1:1000.
Immunohistochemistry-Paraffin: AG-3/AGR3 Antibody [NBP2-15307]

Immunohistochemistry-Paraffin: AG-3/AGR3 Antibody [NBP2-15307]

Immunohistochemistry-Paraffin: AG-3/AGR3 Antibody [NBP2-15307] - Paraffin-embedded rat colon diluted at 1:500.
Immunohistochemistry: AG-3/AGR3 Antibody [NBP2-15307]

Immunohistochemistry: AG-3/AGR3 Antibody [NBP2-15307]

Immunohistochemistry: AG-3/AGR3 Antibody [NBP2-15307] - Paraffin-embedded HBL435 xenograft; antibody dilution 1:500.

Applications for AG-3/AGR3 Antibody

Application
Recommended Usage

Immunohistochemistry

10 - 1:500

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: AG-3

AGR3 is a gene that encodes Anterior Gradient Homolog 3, a protein associated with breast cancer. Also known as Breat Cancer Membrane Protein 11, AG3 has a positive correlation with the expression of estrogen receptor. Its expression is negatively correlated with the expression of the EGF receptor. Because it is expressed in nearly three-quarters of breast cancer cells, it has high potential as a target for breast cancer therapy.

Long Name

Anterior Gradient 3 Homolog

Alternate Names

AG3, AGR3, BCMP11, PDIA18

Gene Symbol

AGR3

UniProt

Additional AG-3 Products

Product Documents for AG-3/AGR3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for AG-3/AGR3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.