AG-3/AGR3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-47555

Novus Biologicals, part of Bio-Techne
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NBP2-47555
NBP2-47555-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all AG-3 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: WGDDITWVQTYEEGLFYAQKSKKPLMV

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (89%), Rat (89%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for AG-3/AGR3 Antibody

Immunohistochemistry-Paraffin: AG-3/AGR3 Antibody [NBP2-47555]

Immunohistochemistry-Paraffin: AG-3/AGR3 Antibody [NBP2-47555]

Immunohistochemistry-Paraffin: AG-3/AGR3 Antibody [NBP2-47555] - Staining in human fallopian tube and liver tissues using anti-AGR3 antibody. Corresponding AGR3 RNA-seq data are presented for the same tissues.
Immunocytochemistry/ Immunofluorescence: AG-3/AGR3 Antibody [NBP2-47555]

Immunocytochemistry/ Immunofluorescence: AG-3/AGR3 Antibody [NBP2-47555]

Immunocytochemistry/Immunofluorescence: AG-3/AGR3 Antibody [NBP2-47555] - Staining of human cell line U-2 OS shows localization to endoplasmic reticulum & vesicles. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: AG-3/AGR3 Antibody [NBP2-47555]

Immunohistochemistry-Paraffin: AG-3/AGR3 Antibody [NBP2-47555]

Immunohistochemistry-Paraffin: AG-3/AGR3 Antibody [NBP2-47555] - Staining of human fallopian tube shows high expression.
View 1 more images

Applications for AG-3/AGR3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF,Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: AG-3

AGR3 is a gene that encodes Anterior Gradient Homolog 3, a protein associated with breast cancer. Also known as Breat Cancer Membrane Protein 11, AG3 has a positive correlation with the expression of estrogen receptor. Its expression is negatively correlated with the expression of the EGF receptor. Because it is expressed in nearly three-quarters of breast cancer cells, it has high potential as a target for breast cancer therapy.

Long Name

Anterior Gradient 3 Homolog

Alternate Names

AG3, AGR3, BCMP11, PDIA18

Gene Symbol

AGR3

Additional AG-3 Products

Product Documents for AG-3/AGR3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for AG-3/AGR3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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