AGAP2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-32176

Novus Biologicals, part of Bio-Techne
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NBP2-32176
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all AGAP2 Antibodies »

Product Specifications

Immunogen

The immunogen this antibody was made to, maps to a region between residue 700 to 750 of human Phosphatidylinositol-3-kinase Enhancer using the numbering given in entry NP_055585.1 (GeneID 116986).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for AGAP2 Antibody

Immunoprecipitation: AGAP2 Antibody [NBP2-32176]

Immunoprecipitation: AGAP2 Antibody [NBP2-32176]

Immunoprecipitation: AGAP2 Antibody [NBP2-32176] - Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from Jurkat cells. Antibodies: Affinity purified rabbit anti-AGAP2 antibody NBP2-32176 used for IP at 6 ug per reaction. For blotting immunoprecipitated AGAP2 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.

Applications for AGAP2 Antibody

Application
Recommended Usage

Immunoprecipitation

2 - 10 ug/mg lysate

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: AGAP2

AGAP2 (also known as centaurin-gamma1, ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2, Phosphatidyl-inositol-3-kinase enhancer, PIKE, GTP-binding and GTPase activating protein 2 and GGAP2) is a GTPase activating protein that inactivates Arf. The expression of AGAP2 is amplified in human glioblastoma cells. AGAP2 protein binds to and activates the protein kinase Akt and prevents apoptosis of cancer cells. AGAP2 also increases motility and invasive activity of cancer cells. AGAP2 may serve as a diagnostic and therapeutic target of human cancer.

Alternate Names

AGAP-2, ArfGAP with GTPase domain, ankyrin repeat and PH domain 2, arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2, centaurin, gamma 1, Centaurin-gamma-1, CENTG1, cnt-g1, FLJ16430, GGAP2, GTP-binding and GTPase activating protein 2, GTP-binding and GTPase-activating protein 2, KIAA0167, Phosphatidylinositol-3-kinase enhancer, phosphoinositide 3-kinase enhancer, PIKEArf GAP with GTP-binding protein-like, ANK repeat and PH domains 2

Gene Symbol

AGAP2

UniProt

NP_055585.1 (Human)

Additional AGAP2 Products

Product Documents for AGAP2 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for AGAP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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