AGTR-1 Antibody (S07-1I6)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19499

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S07-1I6

Concentration

0.3 mg/ml

View all AGTR-1 Antibodies »

Product Specifications

Immunogen

A synthetic peptide of human AGTR-1 (Uniprot # P30556)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

41 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for AGTR-1 Antibody (S07-1I6)

Western Blot: AGTR-1 Antibody (S07-1I6) [NBP3-19499]

Western Blot: AGTR-1 Antibody (S07-1I6) [NBP3-19499]

Western Blot: AGTR-1 Antibody (S07-1I6) [NBP3-19499] - Western blot detection of AGTR-1 in HepG2 cell lysates using NBP3-19499 (1:1000 diluted). Predicted band size: 41kDa. Observed band size: 41kDa.

Applications for AGTR-1 Antibody (S07-1I6)

Application
Recommended Usage

Western Blot

1/1000-1/5000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: AGTR-1

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. At least four transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants.

Long Name

Angiotensin II Receptor Type 1

Alternate Names

AG2S, AGTR1, AT1, AT1AR, AT1BR, AT1R, AT2R1

Gene Symbol

AGTR1

Additional AGTR-1 Products

Product Documents for AGTR-1 Antibody (S07-1I6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for AGTR-1 Antibody (S07-1I6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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