AGTR-1 Antibody [CoraFluor™ 1]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77078CL1

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP1-77078AF350

Alexa Fluor 405

NBP1-77078AF405

Alexa Fluor 488

NBP1-77078AF488

Alexa Fluor 532

NBP1-77078AF532

Alexa Fluor 594

NBP1-77078AF594

Alexa Fluor 647

NBP1-77078AF647

Alexa Fluor 700

NBP1-77078AF700

Alexa Fluor 750

NBP1-77078AF750

Biotin

NBP1-77078B

DyLight 350

NBP1-77078UV

DyLight 405

NBP1-77078V

DyLight 488

NBP1-77078G

DyLight 550

NBP1-77078R

DyLight 594

NBP1-77078DL594

DyLight 650

NBP1-77078C

DyLight 680

NBP1-77078FR

DyLight 755

NBP1-77078IR

FITC

NBP1-77078F

HRP

NBP1-77078H

Janelia Fluor 525

NBP1-77078JF525

Janelia Fluor 549

NBP1-77078JF549

Janelia Fluor 585

NBP1-77078JF585

Janelia Fluor 635

NBP1-77078JF635

Janelia Fluor 646

NBP1-77078JF646

Janelia Fluor 669

NBP1-77078JF669

mFluor Violet 450 SE

NBP1-77078MFV450

mFluor Violet 500 SE

NBP1-77078MFV500

mFluor Violet 610 SE

NBP1-77078MFV610

PerCP

NBP1-77078PCP

Forumulation

Catalog #

BSA Free

NBP1-77078

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Rabbit

Predicted:

Bovine (94%), Guinea Pig (100%), Porcine (100%), Rabbit (100%), Sheep (94%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

CoraFluor 1

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all AGTR-1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 16 amino acid synthetic peptide from near the center of human AGTR1. The immunogen is located within amino acids 210 - 260 of AGTR1. Amino Acid Squence: KKAYEIQKNKPRNDDI

Reactivity Notes

Use in Rabbit reported in scientific literature (PMID:35372645).Immunogen displays the following percentage of sequence identity for non-tested species: Chicken (81%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.

Applications for AGTR-1 Antibody [CoraFluor™ 1]

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: AGTR-1

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. At least four transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants.

Long Name

Angiotensin II Receptor Type 1

Alternate Names

AG2S, AGTR1, AT1, AT1AR, AT1BR, AT1R, AT2R1

Gene Symbol

AGTR1

Additional AGTR-1 Products

Product Documents for AGTR-1 Antibody [CoraFluor™ 1]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for AGTR-1 Antibody [CoraFluor™ 1]

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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