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AGTR-2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77368

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Rabbit

Cited:

Human, Mouse, Rat, Rabbit

Predicted:

Sheep (100%). Backed by our 100% Guarantee.

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

IF/IHC, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

AGTR2 antibody was raised against a 16 amino acid synthetic peptide from near the center of human AGTR2. The immunogen is located within amino acids 220 - 270 of AGTR2. Amino Acid Squence: LKTNSYGKNRITRDQV

Reactivity Notes

Use in Rabbit reported in scientific literature (PMID:35372645).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

36 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for AGTR-2 Antibody - BSA Free

Western Blot: AGTR-2 AntibodyBSA Free [NBP1-77368]

Western Blot: AGTR-2 AntibodyBSA Free [NBP1-77368]

Western Blot: AGTR-2 Antibody [NBP1-77368] - Mouse liver tissue lysate with Angiotensin II Type 2 Receptor antibody at 0.5 ug/ml.
Immunocytochemistry/ Immunofluorescence: AGTR-2 Antibody - BSA Free [NBP1-77368]

Immunocytochemistry/ Immunofluorescence: AGTR-2 Antibody - BSA Free [NBP1-77368]

Immunocytochemistry/Immunofluorescence: AGTR-2 Antibody [NBP1-77368] - Immunofluorescence of AGTR-2 in Jurkat cells with AGTR-2 Antibody.
Immunohistochemistry: AGTR-2 Antibody - BSA Free [NBP1-77368]

Immunohistochemistry: AGTR-2 Antibody - BSA Free [NBP1-77368]

Immunohistochemistry: AGTR-2 Antibody [NBP1-77368] - Representative immunofluorescent immunohistochemical stained images demonstrating the expression of ATIIR2 [red] on GFAP+ CSCs [green]. Negative control was a GBM tissue section with omission of the primary antibody. Cell nuclei were counterstained with 4', 6'-diamidino-2-phenylindole [blue]. Scale bars: 20 um. Image collected and cropped by CiteAb from the following publication (https://journal.frontiersin.org/Article/10.3389/fsurg.2016.00051/abstract), licensed under a CC-BY license.

Applications for AGTR-2 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

1 ug/mL

Immunohistochemistry

5 ug/ml

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

0.5 ug/ml
Application Notes
Use in ICC/IF reported in scientific literature (PMID 27200356).

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: AGTR-2

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. Like AGTR1, AGTR2 is a seven transmembrane G protein-coupled receptor (GPCR), but AGTR2 does not demonstrate most of the classic features of GPCR signaling. AGTR2 is involved in a wide range of activities, including the induction of neurite outgrowth and the inhibition of cellular proliferation, in addition to the known function of mediation of vasoconstriction.

Long Name

Angiostensin II Type 2 Receptor

Alternate Names

AGTR2, AT2, AT2R, MRX88

Gene Symbol

AGTR2

Additional AGTR-2 Products

Product Documents for AGTR-2 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for AGTR-2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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