AIBZIP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-1015

Novus Biologicals, part of Bio-Techne
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NB100-1015
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all AIBZIP Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-PSGRIRSVLHADEM corresponding to C-Terminus according to NP_570968.1.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for AIBZIP Antibody

Western Blot: AIBZIP Antibody [NB100-1015]

Western Blot: AIBZIP Antibody [NB100-1015]

Western Blot: AIBZIP Antibody [NB100-1015] - Staining (0.5ug/ml) of Human Placenta lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
Immunohistochemistry-Paraffin: AIBZIP Antibody [NB100-1015]

Immunohistochemistry-Paraffin: AIBZIP Antibody [NB100-1015]

Immunohistochemistry-Paraffin: AIBZIP Antibody [NB100-1015] - IHC analysis of AIBZIP in paraffin embedded Human Prostate using this antibody at 2.5ug/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Applications for AIBZIP Antibody

Application
Recommended Usage

Immunohistochemistry

2 - 4 ug/ml

Immunohistochemistry-Paraffin

2 - 4 ug/ml

Peptide ELISA

Detection limit 1:32000

Western Blot

0.5 - 2 ug/ml
Application Notes
WB: Approx. 50 kDa band observed in human placenta lysate (predicted MW of 45 kDa band according to NP_570968). IHC-P: Human prostate shows strong staining of cytoplasm in the secretory cells of the gland.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: AIBZIP

Androgen-induced basic leucine zipper (AIBZIP)is a transcription factor. AIbZIP is a 395 aa protein with homology to cyclic AMP-responsive element binding protein/activating transcription factor. It contains an NH(2)-terminal activation domain, a central bZIP domain, and a COOH-terminal transmembrane domain. Immunoreactive AIbZIP protein has been detected in the cytoplasm of prostatic luminal epithelial cells; full-length AIbZIP-GFP fusion proteins are localized in the cytoplasm of LNCaP cells, while a truncated form of AIbZIP lacking the putative transmembrane domain was exclusively nuclear. AIbZIP is expressed at higher levels in cancerous prostate cells compared with noncancerous prostate cells.

Alternate Names

AIbZIP, AIBZIPcAMP-responsive element-binding protein 4, Androgen-induced basic leucine zipper protein, ATCE1JAL, Attaching to CRE-like 1, cAMP responsive element binding protein 1, cAMP responsive element binding protein 3-like 4, CREB3, CREB4CREB-4, cyclic AMP-responsive element-binding protein 3-like protein 4, Cyclic AMP-responsive element-binding protein 4, hJALcAMP-responsive element-binding protein 3-like protein 4, Tisp40, Transcript induced in spermiogenesis protein 40

Entrez Gene IDs

148327 (Human)

Gene Symbol

CREB3L4

UniProt

Q8TEY5 (Human)

Additional AIBZIP Products

Product Documents for AIBZIP Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for AIBZIP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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