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AIM2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-23347

Novus Biologicals, part of Bio-Techne
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NBP3-23347

Key Product Details

Validated by

Biological Validation

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

AIM2 synthetic peptide (coupled to KLH) corresponds to amino acid residues in the N-terminal region of human AIM2. This peptide sequence is highly conserved in rat and mouse AIM2. [UniProt# O14862]

Specificity

The antibody detects a 40 kDa doublet corresponding to AIM2 in immunoblots of Jurkat cells, as well as mouse macrophages treated with IFN gamma and LPS.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

40 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Stable for at least 1 year at -20°C.

Scientific Data Images for AIM2 Antibody

AIM2 Antibody

Western Blot: AIM2 Antibody [NBP3-23347] -

Western Blot: AIM2 Antibody [NBP3-23347] - Western blot analysis of human Jurkat cells (lane 1), mouse macrophages untreated (lane 2) and treated (lane 3) with IFN gamma (10 ng/ml) and LPS (1ug/ml) for 12 hr (20 ug/lane). The blot was probed with rabbit polyclonal anti-AIM2 (N-terminal region) antibody at 1:1000.
AIM2 Antibody

Western Blot: AIM2 Antibody [NBP3-23347] -

Western Blot: AIM2 Antibody [NBP3-23347] - Western blot analysis of human recombinant AIM2 full length sequence with N-terminal GST tag (62 kDa). The blot was probed with rabbit polyclonal anti-AIM2 (N-terminal region) antibody at 1:250 (lane 1) and 1:1000 (lane 2).

Applications for AIM2 Antibody

Application
Recommended Usage

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS, 1 mg/ml BSA and 50% glycerol

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C.

Background: AIM2

AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2.

Long Name

Absent In Melanoma 2

Alternate Names

Gm1313, Ifi210, PYHIN4

Gene Symbol

AIM2

Additional AIM2 Products

Product Documents for AIM2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for AIM2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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