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ALAS2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-32826

Novus Biologicals, part of Bio-Techne
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NBP1-32826

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for ALAS2 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human ALAS2. The exact sequence is proprietary.

Localization

Mitochondrion matrix

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ALAS2 Antibody

Western Blot: ALAS2 Antibody [NBP1-32826]

Western Blot: ALAS2 Antibody [NBP1-32826]

Western Blot: ALAS2 Antibody [NBP1-32826] - Sample (50 ug of whole cell lysate) A: mouse liver 7.5% SDS PAGE; antibody diluted at 1:1000.
Western Blot: ALAS2 Antibody [NBP1-32826]

Western Blot: ALAS2 Antibody [NBP1-32826]

Western Blot: ALAS2 Antibody [NBP1-32826] - Sample (30 ug of whole cell lysate) A: K562 7.5% SDS PAGE, antibody diluted at 1:500.
ALAS2 Antibody

Western Blot: ALAS2 Antibody [NBP1-32826] -

Western Blot: ALAS2 Antibody [NBP1-32826] - Various tissue extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with ALAS2 antibody [N3C3] (NBP1-32826) diluted at 1:500.

Applications for ALAS2 Antibody

Application
Recommended Usage

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: ALAS2

The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternate Names

5-aminolevulinic acid synthase 2,5-aminolevulinate synthase, erythroid-specific, mitochondrial, ALASE, ALAS-E, aminolevulinate, delta-, synthase 2, aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia), ANH1, ASBXLDPP, Delta-ALA synthase 2, delta-ALA synthetase, Delta-aminolevulinate synthase 2, EC 2.3.1.37, FLJ93603, XLSA

Gene Symbol

ALAS2

Additional ALAS2 Products

Product Documents for ALAS2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ALAS2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.