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ALDH2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-14280

Novus Biologicals, part of Bio-Techne
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NBP2-14280

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (92%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for ALDH2 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LLSAAATQAVPAPNQQPEVFCNQI

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ALDH2 Antibody

Western Blot: ALDH2 Antibody [NBP2-14280]

Western Blot: ALDH2 Antibody [NBP2-14280]

Western Blot: ALDH2 Antibody [NBP2-14280] - Analysis in human liver tissue.
Immunohistochemistry-Paraffin: ALDH2 Antibody [NBP2-14280]

Immunohistochemistry-Paraffin: ALDH2 Antibody [NBP2-14280]

Immunohistochemistry-Paraffin: ALDH2 Antibody [NBP2-14280] - Staining of human heart shows no cytoplasmic positivity in myocytes as expected.
Immunohistochemistry-Paraffin: ALDH2 Antibody [NBP2-14280]

Immunohistochemistry-Paraffin: ALDH2 Antibody [NBP2-14280]

Immunohistochemistry-Paraffin: ALDH2 Antibody [NBP2-14280] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules.

Applications for ALDH2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ALDH2

ALDH2 belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. [provided by RefSeq]

Long Name

Aldehyde Dehydrogenase 2 Family Member

Alternate Names

ALDHI, ALDM

Gene Symbol

ALDH2

Additional ALDH2 Products

Product Documents for ALDH2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ALDH2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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