ALDH8A1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89151

Novus Biologicals, part of Bio-Techne
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NBP1-89151
NBP1-89151-25ul
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Key Product Details

Validated by

Orthogonal Validation, Independent Antibodies

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ALDH8A1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LPCSSYIDSYDPSTGEVYCRVPNSGKDEIEAAVKAAREAFPSWSSRSPQERSRVLNQVADLLEQS

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (86%), Rat (85%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ALDH8A1 Antibody

Immunohistochemistry-Paraffin: ALDH8A1 Antibody [NBP1-89151]

Immunohistochemistry-Paraffin: ALDH8A1 Antibody [NBP1-89151]

Immunohistochemistry-Paraffin: ALDH8A1 Antibody [NBP1-89151] - Staining of human lymph node.
Immunohistochemistry-Paraffin: ALDH8A1 Antibody [NBP1-89151]

Immunohistochemistry-Paraffin: ALDH8A1 Antibody [NBP1-89151]

Immunohistochemistry-Paraffin: ALDH8A1 Antibody [NBP1-89151] - Staining of human liver shows high expression.
Immunohistochemistry-Paraffin: ALDH8A1 Antibody [NBP1-89151]

Immunohistochemistry-Paraffin: ALDH8A1 Antibody [NBP1-89151]

Immunohistochemistry-Paraffin: ALDH8A1 Antibody [NBP1-89151] - Staining of human pancreas shows low expression as expected.
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Applications for ALDH8A1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ALDH8A1

ALDH8A1 belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]

Alternate Names

Aldehyde dehydrogenase 12, aldehyde dehydrogenase 8 family, member A1, aldehyde dehydrogenase family protein, ALDH12aldehyde dehydrogenase family 8 member A1, DJ352A20.2, DKFZp779D2315, EC 1.2.1, EC 1.2.1.-, EC 1.2.1.3, MGC138650

Entrez Gene IDs

64577 (Human)

Gene Symbol

ALDH8A1

UniProt

Q9H2A2 (Human)

Additional ALDH8A1 Products

Product Documents for ALDH8A1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ALDH8A1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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