ALMS1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-1195

Novus Biologicals, part of Bio-Techne
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NB100-1195
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Canine (100%), Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all ALMS1 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-RVTNQLLGRKVPWD corresponding to C-Terminus according to NP_055935.4.

Epitope

RVTNQLLGRKVPWD

Specificity

The C terminus of ALMS1 shares an 8 amino acid stretch with two other human proteins: hypothetical protein (XP_169104) and ERAL1 (NP_005693). However, this stretch is located internally in these two proteins and so will most likely not cross-react with this antibody. The N terminus was not chosen as the peptide is expected to cyclise during synthesis.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for ALMS1 Antibody

Immunocytochemistry/ Immunofluorescence: ALMS1 Antibody [NB100-1195]

Immunocytochemistry/ Immunofluorescence: ALMS1 Antibody [NB100-1195]

Immunocytochemistry/Immunofluorescence: ALMS1 Antibody [NB100-1195] - Immunofluorescence analysis of paraformaldehyde fixed HepG2 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL), showing cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2 ug/mL).
Immunocytochemistry/ Immunofluorescence: ALMS1 Antibody [NB100-1195]

Immunocytochemistry/ Immunofluorescence: ALMS1 Antibody [NB100-1195]

Immunocytochemistry/Immunofluorescence: ALMS1 Antibody [NB100-1195] - Immunofluorescence analysis of paraformaldehyde fixed HeLa cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL), showing cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL).

Applications for ALMS1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

10 ug/mL

Peptide ELISA

Detection limit 1:4000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: ALMS1

This protein contains a large tandem-repeat domain that contains no cysteine residues. Mutations in this gene have been associated with Alstrom syndrome. The encoded protein may play a role in hearing, sight, obesity, and liver function. Alternative splice variants have been described but their full length sequences have not been determined.

Alternate Names

Alstrom syndrome 1, Alstrom syndrome protein 1, DKFZp686A118, DKFZp686D1828, KIAA0328ALSS

Entrez Gene IDs

7840 (Human); 236266 (Mouse); 297408 (Rat)

Gene Symbol

ALMS1

UniProt

NP_055935 (Human)

Additional ALMS1 Products

Product Documents for ALMS1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for ALMS1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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