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ALMS1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-83015

Novus Biologicals, part of Bio-Techne
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NBP1-83015
NBP1-83015-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for ALMS1 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: DFFQHHPDKHREHMCLPLPYQNMDKTKTDYTRIKSLSINVNLGNKEVMDTTKSQVRDYPKHNGQISDPQRDQKVTP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ALMS1 Antibody

Immunocytochemistry/ Immunofluorescence: ALMS1 Antibody [NBP1-83015]

Immunocytochemistry/ Immunofluorescence: ALMS1 Antibody [NBP1-83015]

Immunocytochemistry/Immunofluorescence: ALMS1 Antibody [NBP1-83015] - Immunofluorescent staining of human cell line A-431 shows localization to cytosol.
Immunohistochemistry-Paraffin: ALMS1 Antibody [NBP1-83015]

Immunohistochemistry-Paraffin: ALMS1 Antibody [NBP1-83015]

Immunohistochemistry-Paraffin: ALMS1 Antibody [NBP1-83015] - Staining in human testis and skeletal muscle tissues using anti-ALMS1 antibody. Corresponding ALMS1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: ALMS1 Antibody [NBP1-83015]

Immunohistochemistry-Paraffin: ALMS1 Antibody [NBP1-83015]

Immunohistochemistry-Paraffin: ALMS1 Antibody [NBP1-83015] - Staining of human skeletal muscle shows low expression as expected.

Applications for ALMS1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ALMS1

Mutations in the ALMS1 gene are the cause of Alstrom syndrome, a rare autosomal recessive disease characterized by type 2 diabetes mellitus, obesity, cardiomyopathy, and neurosensory defects such as cone-rod retinal dystrophy, and hearing loss. In the cell, ALMS1 localizes to basal bodies of ciliated cells and centrosomes and is thus a member of proteins associated with genetic ciliopathies. ALMS1 is also known as KIAA0328 and ALSS.

Alternate Names

Alstrom syndrome 1, Alstrom syndrome protein 1, DKFZp686A118, DKFZp686D1828, KIAA0328ALSS

Gene Symbol

ALMS1

Additional ALMS1 Products

Product Documents for ALMS1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ALMS1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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