alpha-1B Adrenergic R/ADRA1B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-26181

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Porcine

Predicted:

Bovine (100%), Canine (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all alpha-1B Adrenergic R/ADRA1B Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-SSTKAKGHNPRSS corresponding to internal region according to NP_000670.1.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for alpha-1B Adrenergic R/ADRA1B Antibody

Western Blot: alpha-1B Adrenergic R/ADRA1B Antibody [NBP2-26181]

Western Blot: alpha-1B Adrenergic R/ADRA1B Antibody [NBP2-26181]

Western Blot: alpha-1B Adrenergic R/ADRA1B Antibody [NBP2-26181] - Human Heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Western Blot: alpha-1B Adrenergic R/ADRA1B Antibody [NBP2-26181]

Western Blot: alpha-1B Adrenergic R/ADRA1B Antibody [NBP2-26181]

Western Blot: alpha-1B Adrenergic R/ADRA1B Antibody [NBP2-26181] - Pig Heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for alpha-1B Adrenergic R/ADRA1B Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:128000

Western Blot

0.1 - 0.3 ug/ml
Application Notes
WB: Approx. 55-60 kDa band observed in human, mouse, rat and porcine heart lysates (calculated MW of 56.8 kDa band according to NP_000670.1).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: alpha-1B Adrenergic R/ADRA1B

The alpha-1b adrenoceptor is an Adrenergic Receptor that causes contraction of smooth muscle cells and thereby controls vascular tone, blood pressure, and accelerates the development of atherosclerosis. Decreased alpha-1b adrenoceptor is associated with benign prostatic hyperplasia (BPH). This adrenergic receptor also acts as a proto-oncogene when transfected into cell lines where constitutive activation of the receptor induces neoplastic transformation. The alpha-1b adrenoceptor has been documented in adrenal, aorta, blood, various brain regions, eye, heart, kidney, liver, prostate, spinal cord, and spleen. ESTs have been isolated from kidney (normal and cancer) and lung carcinoma libraries.

Long Name

Alpha-1B Adrenergic Receptor

Alternate Names

a-1B AdrenergicR, ADRA1B, alpha1B AdrenergicR, ALPHA1BAR

Entrez Gene IDs

147 (Human); 11548 (Mouse); 24173 (Rat)

Gene Symbol

ADRA1B

Additional alpha-1B Adrenergic R/ADRA1B Products

Product Documents for alpha-1B Adrenergic R/ADRA1B Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for alpha-1B Adrenergic R/ADRA1B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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