alpha-1B Adrenergic R/ADRA1B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-57288

Novus Biologicals, part of Bio-Techne
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NBP2-57288
NBP2-57288-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%), Rat (94%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all alpha-1B Adrenergic R/ADRA1B Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: MNPDLDTGHNTSAPAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for alpha-1B Adrenergic R/ADRA1B Antibody

Immunocytochemistry/ Immunofluorescence: alpha-1B Adrenergic R/ADRA1B Antibody [NBP2-57288]

Immunocytochemistry/ Immunofluorescence: alpha-1B Adrenergic R/ADRA1B Antibody [NBP2-57288]

Immunocytochemistry/Immunofluorescence: alpha-1B Adrenergic R/ADRA1B Antibody [NBP2-57288] - Staining of human cell line U-251 MG shows localization to plasma membrane.

Applications for alpha-1B Adrenergic R/ADRA1B Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: alpha-1B Adrenergic R/ADRA1B

The alpha-1b adrenoceptor is an Adrenergic Receptor that causes contraction of smooth muscle cells and thereby controls vascular tone, blood pressure, and accelerates the development of atherosclerosis. Decreased alpha-1b adrenoceptor is associated with benign prostatic hyperplasia (BPH). This adrenergic receptor also acts as a proto-oncogene when transfected into cell lines where constitutive activation of the receptor induces neoplastic transformation. The alpha-1b adrenoceptor has been documented in adrenal, aorta, blood, various brain regions, eye, heart, kidney, liver, prostate, spinal cord, and spleen. ESTs have been isolated from kidney (normal and cancer) and lung carcinoma libraries.

Long Name

Alpha-1B Adrenergic Receptor

Alternate Names

a-1B AdrenergicR, ADRA1B, alpha1B AdrenergicR, ALPHA1BAR

Gene Symbol

ADRA1B

Additional alpha-1B Adrenergic R/ADRA1B Products

Product Documents for alpha-1B Adrenergic R/ADRA1B Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for alpha-1B Adrenergic R/ADRA1B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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