alpha-2B Adrenergic R/ADRA2B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-97424

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all alpha-2B Adrenergic R/ADRA2B Antibodies »

Product Specifications

Immunogen

Produced in rabbits immunized with E. coli-derived Human alpha-2B Adrenergic R/ADRA2B fragment.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for alpha-2B Adrenergic R/ADRA2B Antibody

Western Blot: alpha-2B Adrenergic R/ADRA2B Antibody [NBP2-97424]

Western Blot: alpha-2B Adrenergic R/ADRA2B Antibody [NBP2-97424]

Western Blot: alpha-2B Adrenergic R/ADRA2B Antibody [NBP2-97424] - Anti-alpha-2B Adrenergic R/ADRA2B rabbit polyclonal antibody at 1:500 dilution. Lane A: U-251 MG Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 50 kDa. Observed band size: 54 kDa
Immunohistochemistry-Paraffin: alpha-2B Adrenergic R/ADRA2B Antibody [NBP2-97424]

Immunohistochemistry-Paraffin: alpha-2B Adrenergic R/ADRA2B Antibody [NBP2-97424]

Immunohistochemistry-Paraffin: alpha-2B Adrenergic R/ADRA2B Antibody [NBP2-97424] - Staining of human alpha-2B Adrenergic R/ADRA2B in cynomolgus cerebellum with rabbit polyclonal antibody at 1:200 dilution.

Applications for alpha-2B Adrenergic R/ADRA2B Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:400

Immunohistochemistry-Paraffin

1:100-1:400

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

PBS

Preservative

0.03% Proclin 300

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: alpha-2B Adrenergic R/ADRA2B

Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. This gene encodes the alpha2B subtype, which was observed to associate with eIF-2B, a guanine nucleotide exchange protein that functions in regulation of translation. A polymorphic variant of the alpha2B subtype, which lacks 3 glutamic acids from a glutamic acid repeat element, was identified to have decreased G protein-coupled receptor kinase-mediated phosphorylation and desensitization; this polymorphic form is also associated with reduced basal metabolic rate in obese subjects and may therefore contribute to the pathogenesis of obesity. This gene contains no introns in either its coding or untranslated sequences. (provided by RefSeq)

Long Name

Alpha-2B Adrenergic Receptor

Alternate Names

a-2B AdrenergicR, ADRA2B, ADRA2L1, ADRA2RL1, ADRARL1, alpha2B AdrenergicR

Gene Symbol

ADRA2B

Additional alpha-2B Adrenergic R/ADRA2B Products

Product Documents for alpha-2B Adrenergic R/ADRA2B Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for alpha-2B Adrenergic R/ADRA2B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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