alpha Adaptin Antibody (SR1044)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21875

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21875-100ul
NBP3-21875-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1044

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all alpha Adaptin Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human alpha Adaptin (Uniprot #: O95782)

Specificity

Detects endogenous levels of total alpha Adaptin

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

108 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for alpha Adaptin Antibody (SR1044)

Western Blot: alpha Adaptin Antibody (SR1044) [NBP3-21875] -

Western Blot: alpha Adaptin Antibody (SR1044) [NBP3-21875] - Western blot analysis using NBP3-21875 in A431 cell lysate.

Applications for alpha Adaptin Antibody (SR1044)

Application
Recommended Usage

Flow Cytometry

1:100

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunohistochemistry

1:50-1:200

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: alpha Adaptin

AP2A1, also known as AP-2 complex subunit alpha-1, contains a 208 kDa and a 105 kDa isoform, and is involved in protein transport, vesicle formation, and clathrin-dependent endocytosis. Current research is being conducted on the relationship between AP2A1 and a variety of diseases and disorders, including seminoma, neuronitis, Huntington's disease, malaria, myeloid leukemia, carcinoma, gout, immunodeficiency, pancreatic cancer, prostatitis, prostate carcinoma, cholesterol, breast cancer, leukemia, and pancreatitis. AP2A1 is associated with Clathrin-dependent protein traffic, CTLA4 Signaling, p38 Signaling, the EGFR1 Signaling Pathway, the Synaptic Vesicle Pathway, the Arf1 pathway, and L1CAM interactions. The protein interacts with HIP1, TOE1, SMAD9, NUMB, and GRB2.

Alternate Names

100 kDa coated vesicle protein A, Adapter-related protein complex 2 alpha-1 subunit, Adaptor protein complex AP-2 subunit alpha-1, adaptor-related protein complex 2, alpha 1 subunit, ADTAAAP2-ALPHA, alpha1-adaptin, Alpha-adaptin A, AP-2 complex subunit alpha-1, CLAPA1adaptin, alpha A, Clathrin assembly protein complex 2 alpha-A large chain, clathrin-associated/assembly/adaptor protein, large, alpha 1, Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit

Gene Symbol

AP2A1

Additional alpha Adaptin Products

Product Documents for alpha Adaptin Antibody (SR1044)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for alpha Adaptin Antibody (SR1044)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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