alpha-Defensin 1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-46808

Novus Biologicals, part of Bio-Techne
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NBP2-46808
NBP2-46808-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all alpha-Defensin 1 Antibodies »

Product Summary for alpha-Defensin 1 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: EPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGSRKNMACYCRIPACIAGERRYGTCIYQGRLWAFC

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for alpha-Defensin 1 Antibody

Immunohistochemistry: alpha-Defensin 1 Antibody [NBP2-46808]

Immunohistochemistry: alpha-Defensin 1 Antibody [NBP2-46808]

Immunohistochemistry: alpha-Defensin 1 Antibody [NBP2-46808] - Staining of human bone marrow shows strong cytoplasmic positivity in hematopoietic cells.

Applications for alpha-Defensin 1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: alpha-Defensin 1

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundantin the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine,respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequenceand distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8.The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likelyplays a role in phagocyte-mediated host defense. It differs from defensin, alpha 3 by only one amino acid. (providedby RefSeq)

Alternate Names

alphaDefensin 1, DEF1, DEFA1, HNP-1, HP1, MRS

Entrez Gene IDs

1667 (Human)

Gene Symbol

DEFA1

UniProt

P59665

Additional alpha-Defensin 1 Products

Product Documents for alpha-Defensin 1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for alpha-Defensin 1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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