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alpha-Internexin Antibody (S03-6H1)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19567

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-19567-100ul
NBP3-19567-50ul

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S03-6H1

Concentration

0.3 mg/ml

Product Summary for alpha-Internexin Antibody (S03-6H1)

Immunogen

A synthetic peptide of human alpha-Internexin (Uniprot # Q16352)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

55 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for alpha-Internexin Antibody (S03-6H1)

Western Blot: alpha-Internexin Antibody (S03-6H1) [NBP3-19567]

Western Blot: alpha-Internexin Antibody (S03-6H1) [NBP3-19567]

Western Blot: alpha-Internexin Antibody (S03-6H1) [NBP3-19567] - Western blot detection of alpha-Internexin in Hela cell lysates using NBP3-19567 (1:1000 diluted). Predicted band size: 55kDa. Observed band size: 55kDa.

Applications for alpha-Internexin Antibody (S03-6H1)

Application
Recommended Usage

Western Blot

1/2000-1/10000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: alpha-Internexin

Alpha-internexin is a Class IV intermediate filament, related to but distinct from the better known neurofilament triplet proteins, NF-L, NF-M and NF-H. It is expressed only in neurons and in large amounts early in neuronal development, but is down-regulated in many neurons as development procedes. However, many classes of mature neurons contain alpha-internexin in addition to NF-L, NF-M and NF-H, and some mature neurons only express the alpha-internexin subunit of neurofilament.

The very early developmental expression of alpha-internexin suggests that its presence is an early and convenient diagnostic feature of neuronal progenitors cells and other cell committed to the neuronal lineage. Therefore, alpha-internexin antibodies serve as unique probes to study and classify neuronal types and follow their processes in tissue sections and culture.

Alternate Names

alphaInternexin, INA, NEF5, NF-66, TXBP-1

Gene Symbol

INA

Additional alpha-Internexin Products

Product Documents for alpha-Internexin Antibody (S03-6H1)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for alpha-Internexin Antibody (S03-6H1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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