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Alpha-mannosidase II Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89748

Novus Biologicals, part of Bio-Techne
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NBP1-89748
NBP1-89748-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LVVYNPLEQDRISLVSVYVSSPTVQVFSASGKPVEVQVSAVWDTANTISETAYEISFRAHIPPLGLKVYKILESASSNSHLADYVLYKNKVEDSGIFTIKNMINTEEGITLENSFVLLRFDQTGLMKQMMTKED

Marker

Golgi Apparatus Marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Alpha-mannosidase II Antibody

Immunohistochemistry-Paraffin: Alpha-mannosidase II Antibody [NBP1-89748]

Immunohistochemistry-Paraffin: Alpha-mannosidase II Antibody [NBP1-89748]

Immunohistochemistry-Paraffin: Alpha-mannosidase II Antibody [NBP1-89748] - Staining of human skeletal muscle shows low expression as expected.
Immunohistochemistry-Paraffin: Alpha-mannosidase II Antibody [NBP1-89748]

Immunohistochemistry-Paraffin: Alpha-mannosidase II Antibody [NBP1-89748]

Immunohistochemistry-Paraffin: Alpha-mannosidase II Antibody [NBP1-89748] - Staining of human gallbladder shows strong cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: Alpha-mannosidase II Antibody [NBP1-89748]

Immunohistochemistry-Paraffin: Alpha-mannosidase II Antibody [NBP1-89748]

Immunohistochemistry-Paraffin: Alpha-mannosidase II Antibody [NBP1-89748] - Staining of human parathyroid gland shows high expression.

Applications for Alpha-mannosidase II Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Alpha-mannosidase II

Alpha-mannosidase II encodes a protein which is a member of family 38 of the glycosyl hydrolases. The protein is located in the Golgi and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-glycan) maturation pathway. Mutations in the mouse homolog of this gene have been shown to cause a systemic autoimmune disease similar to human systemic lupus erythematosus. [provided by RefSeq]

Alternate Names

alpha-mannosidase 2, AMan II, EC 3.2.1, EC 3.2.1.114, Golgi alpha-mannosidase II, golgi integral membrane protein 7, GOLIM7, Man II, MANA2MANII, Mannosidase alpha class 2A member 1, mannosidase, alpha type II, mannosidase, alpha, class 2A, member 1, Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase

Gene Symbol

MAN2A1

Additional Alpha-mannosidase II Products

Product Documents for Alpha-mannosidase II Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Alpha-mannosidase II Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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