alpha-N-acetylglucosaminidase/NAGLU Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-82601

Novus Biologicals, part of Bio-Techne
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NBP1-82601
NBP1-82601-25ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all alpha-N-acetylglucosaminidase/NAGLU Antibodies »

Product Summary for alpha-N-acetylglucosaminidase/NAGLU Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LQGWLFQHQPQFWGPAQIRAVLGAVPRGRLLVLDLFAESQPVYTRTASFQGQPFIWCMLHNFGGNHGLFGALEAVNGGPEAARLFPNSTMVGTGMAPEGISQNEVVYSLMA

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (89%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for alpha-N-acetylglucosaminidase/NAGLU Antibody

Immunohistochemistry: alpha-N-acetylglucosaminidase/NAGLU Antibody [NBP1-82601]

Immunohistochemistry: alpha-N-acetylglucosaminidase/NAGLU Antibody [NBP1-82601]

Immunohistochemistry: alpha-N-acetylglucosaminidase/NAGLU Antibody [NBP1-82601] - Staining of mouse nucleus ambiguus and lateral paragigantocellular nucleus shows positivity in neurons.
Immunohistochemistry-Paraffin: alpha-N-acetylglucosaminidase/NAGLU Antibody [NBP1-82601]

Immunohistochemistry-Paraffin: alpha-N-acetylglucosaminidase/NAGLU Antibody [NBP1-82601]

Immunohistochemistry-Paraffin: alpha-N-acetylglucosaminidase/NAGLU Antibody [NBP1-82601] - Staining of human testis shows strong cytoplasmic positivity in seminiferus ducts and leydig cells.
Immunohistochemistry-Paraffin: alpha-N-acetylglucosaminidase/NAGLU Antibody [NBP1-82601]

Immunohistochemistry-Paraffin: alpha-N-acetylglucosaminidase/NAGLU Antibody [NBP1-82601]

Immunohistochemistry-Paraffin: alpha-N-acetylglucosaminidase/NAGLU Antibody [NBP1-82601] - Staining of human lateral ventricle shows cytoplasmic positivity in neurons.
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Applications for alpha-N-acetylglucosaminidase/NAGLU Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: alpha-N-acetylglucosaminidase/NAGLU

NAGLU encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate. [provided by RefSeq]

Alternate Names

alphaNacetylglucosaminidase, NAG, NAGLU, UFHSD1

Gene Symbol

NAGLU

Additional alpha-N-acetylglucosaminidase/NAGLU Products

Product Documents for alpha-N-acetylglucosaminidase/NAGLU Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for alpha-N-acetylglucosaminidase/NAGLU Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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