AMCase/CHIA Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-15880

Novus Biologicals, part of Bio-Techne
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NBP2-15880
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all AMCase/CHIA Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human AMCase/CHIA. The exact sequence is proprietary.

Localization

Secreted; Isoform 2: Cytoplasm; Isoform 3: Cytoplasm

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

40 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for AMCase/CHIA Antibody

Western Blot: AMCase/CHIA Antibody [NBP2-15880]

Western Blot: AMCase/CHIA Antibody [NBP2-15880]

Western Blot: AMCase/CHIA Antibody [NBP2-15880] - Sample (30 ug of whole cell lysate) A: JurKat 10% SDS PAGE gel, diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: AMCase/CHIA Antibody [NBP2-15880]

Immunocytochemistry/ Immunofluorescence: AMCase/CHIA Antibody [NBP2-15880]

Immunocytochemistry/Immunofluorescence: AMCase/CHIA Antibody [NBP2-15880] - Analysis of methanol-fixed A431, using antibody at 1:500 dilution.

Applications for AMCase/CHIA Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: AMCase/CHIA

Degrades chitin and chitotriose. May participate in the defense against nematodes, fungi and other pathogens. Plays a role in T helper cell type 2 (Th2) immune response. Contributes to the response to IL-13 and inflammation in response to IL-13. Stimulates chemokine production by pulmonary epithelial cells. Protects lung epithelial cells against apoptosis and promotes phosphorylation of AKT1. Its function in the inflammatory response and in protecting cells against apoptosis is inhibited by allosamidin, suggesting that the function of this protein depends on carbohydrate binding.

Long Name

Acidic Mammalian Chitinase

Alternate Names

CHIA, CHIT2, Chitinase, Acidic, Lung-Specific Protein TSA1902

Gene Symbol

CHIA

UniProt

Q9BZP6 (Human)

Additional AMCase/CHIA Products

Product Documents for AMCase/CHIA Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for AMCase/CHIA Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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