Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI1A8

Concentration

1 mg/ml

View all Angiomotin Antibodies »

Product Specifications

Immunogen

Full length human recombinant protein of human AMOT(NP_573572) produced in HEK293T cell.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

72.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for AMOT Antibody (OTI1A8)

Western Blot: AMOT Antibody (OTI1A8) [NBP2-46515]

Western Blot: AMOT Antibody (OTI1A8) [NBP2-46515]

Western Blot: AMOT Antibody (OTI1A8) [NBP2-46515] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY AMOT.
Immunofluorescence: AMOT Antibody (OTI1A8) [NBP2-46515]

Immunofluorescence: AMOT Antibody (OTI1A8) [NBP2-46515]

Immunofluorescence: AMOT Antibody (OTI1A8) [NBP2-46515] - Analysis of COS7 cells transiently transfected by pCMV6-ENTRY AMOT.

Applications for AMOT Antibody (OTI1A8)

Application
Recommended Usage

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Angiomotin

AMOT belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]

Alternate Names

AMOT, CAG-2

Gene Symbol

AMOT

Additional Angiomotin Products

Product Documents for AMOT Antibody (OTI1A8)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for AMOT Antibody (OTI1A8)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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