Amphiregulin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87071

Novus Biologicals, part of Bio-Techne
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NBP1-87071
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Amphiregulin Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: FSGDHSADGFEVTSRSEMSSGSEISPVSEMPSSSEPSSGADYDYSEEYDNEPQIPGYIVDDSVRVEQVVKPPQNKTESENTSDKPKRKKKGGKNGKNRRNRKKKNPCNAEFQNFCIHGECKYIEHLEAVTCKCQQEYFGERC

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 25713333).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Amphiregulin Antibody

Immunohistochemistry-Paraffin: Amphiregulin Antibody [NBP1-87071]

Immunohistochemistry-Paraffin: Amphiregulin Antibody [NBP1-87071]

Immunohistochemistry-Paraffin: Amphiregulin Antibody [NBP1-87071] - Staining of human testis shows weak membranous /cytoplasmic positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: Amphiregulin Antibody [NBP1-87071]

Immunohistochemistry-Paraffin: Amphiregulin Antibody [NBP1-87071]

Immunohistochemistry-Paraffin: Amphiregulin Antibody [NBP1-87071] - Staining of human placenta shows strong membranous positivity in cytotrophoblastic cells.
Immunohistochemistry-Paraffin: Amphiregulin Antibody [NBP1-87071]

Immunohistochemistry-Paraffin: Amphiregulin Antibody [NBP1-87071]

Immunohistochemistry-Paraffin: Amphiregulin Antibody [NBP1-87071] - Staining of human Fallopian tube shows moderate membranous/cytoplasmic positivity in glandular cells.
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Applications for Amphiregulin Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
IHC reported in scientific literature (PMID: 25713333). For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Amphiregulin

The protein encoded by the Amphiregulin gene is a member of the epidermal growth factor family. It is an autocrine growth factor aswell as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) andtransforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote thegrowth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This encodedprotein is associated with a psoriasis-like skin phenotype. (provided by RefSeq)

Alternate Names

AREG

Entrez Gene IDs

374 (Human)

Gene Symbol

AREG

UniProt

P15514

Additional Amphiregulin Products

Product Documents for Amphiregulin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Amphiregulin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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