ANAPC2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-56603

Novus Biologicals, part of Bio-Techne
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NBP2-56603
NBP2-56603-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (95%), Rat (95%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ANAPC2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: REEVHTMLRGVLFFSTPRTFQEMIQRLYGCFLRVYMQSKRKGEGGTDPELEGELDSRYARRRYYRLLQSPLCAGCSSDKQQCWCR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ANAPC2 Antibody

Immunocytochemistry/ Immunofluorescence: ANAPC2 Antibody [NBP2-56603]

Immunocytochemistry/ Immunofluorescence: ANAPC2 Antibody [NBP2-56603]

Immunocytochemistry/Immunofluorescence: ANAPC2 Antibody [NBP2-56603] - Staining of human cell line MCF7 shows localization to nucleoplasm. Antibody staining is shown in green.

Applications for ANAPC2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ANAPC2

ANAPC2 is a large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation.

Alternate Names

anaphase promoting complex subunit 2, anaphase-promoting complex subunit 2, APC2KIAA1406Cyclosome subunit 2, RP11-350O14.5

Gene Symbol

ANAPC2

Additional ANAPC2 Products

Product Documents for ANAPC2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ANAPC2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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