Angiotensin I Antibody (BGN/KA/4H) - BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NB100-62344
Key Product Details
Species Reactivity
Validated:
Human, Rat
Cited:
Human, Rat
Applications
Validated:
ELISA, Western Blot
Cited:
Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG2A Clone # BGN/KA/4H
Format
BSA Free
Concentration
1.0 mg/ml
Product Specifications
Immunogen
Synthetic peptide corresponding to amino acids 40-49 of the angiotensinogen precursor (Swiss-Prot entry P01019) conjugated to HMW carrier protein.
Epitope
P-F-H-L-V-I-H-N-E-S(-C)
Reactivity Notes
Use in Rat reported in scientific literature (PMID:33028854).
Specificity
NB100-62344 is specific for Angiotensin I and does not react with angiotensin II, III or angiotensinogen in ELISA. Enzyme (ACE) into a vasoactive form called Angiotensin II which is responsible for increasing blood pressure. Angiotensin I is important in the Renin-Angiotensin-Aldosterone System (RAAS). RAAS is responsible for the regulation of blood pressure and water retention in the body. Angiotensin I is produced from a reaction between the renal enzyme Renin and angiotensinogen. It is converted by Angiotensin Converting Enzyme (ACE) into a vasoactive form called Angiotensin II which is responsible for increasing blood pressure.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2A
Applications for Angiotensin I Antibody (BGN/KA/4H) - BSA Free
Application
Recommended Usage
ELISA
1:12000-1:100000
Application Notes
Use in Western Blot reported in scientific literature (PMID:33028854).
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A purified
Formulation
PBS
Format
BSA Free
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: Angiotensin I
Alternate Names
alpha-1 antiproteinase, antitrypsin, angiotensin II, angiotensinogen, angiotensinogen (serpin peptidase inhibitor, clade A, member 8), ANHU, FLJ92595, FLJ97926, pre-angiotensinogen, serine (or cysteine) proteinase inhibitor, Serpin A8, SERPINA8angiotensin I
Entrez Gene IDs
183 (Human)
Gene Symbol
AGT
UniProt
Additional Angiotensin I Products
Product Documents for Angiotensin I Antibody (BGN/KA/4H) - BSA Free
Product Specific Notices for Angiotensin I Antibody (BGN/KA/4H) - BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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