Anthrax LF Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56666

Novus Biologicals, part of Bio-Techne
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NB100-56666
NB100-56666SS
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

View all Anthrax LF Antibodies »

Product Specifications

Immunogen

The antibody was developed by immunizing rabbits with synthetic peptides corresponding to amino acids 47-65 of the Anthrax LF protein (approx. 90 kD).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Anthrax LF Antibody

Western Blot: Anthrax LF Antibody [NB100-56666]

Western Blot: Anthrax LF Antibody [NB100-56666]

Western Blot: Anthrax LF Antibody [NB100-56666] - analysis of Anthrax LF in recombinant protein using this antibody. Lane A shows the pre-bleed.

Applications for Anthrax LF Antibody

Application
Recommended Usage

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Whole antisera with PBS and 0.2% Gelatin

Preservative

0.05% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Anthrax LF

Anthrax PA (Protective Antigen) and Anthrax LF (Lethal Factor), along with Anthrax EF (Edema Factor), are toxins produced by Bacillus anthracis. All three of the proteins must be present for toxicity to occur. It begins with the binding of PA to its cell-surface receptor, ATR (Anthrax Toxin Receptor), at which point PA is cleaved and the resulting 63 kD carboxyl-terminal fragment binds to LF and EF. LF is a protease that is known to cleave members of the mitogen-activated protein kinase kinase (MAPKK) family (2).

Alternate Names

Anthrax lethal factor, Anthrax lethal toxin endopeptidase component, Anthrax LF, B.anthracis lethal factor, bacillus anthracis lethal factor, Lef, LF

Additional Anthrax LF Products

Product Documents for Anthrax LF Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Anthrax LF Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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