Antizyme inhibitor 1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-82497

Novus Biologicals, part of Bio-Techne
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NBP1-82497
NBP1-82497-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (97%), Rat (94%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Antizyme inhibitor 1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: AKVGVNILTCDNEIELKKIARNHPNAKVLLHIATEDNIGGEEGNMKFGTTLKNCRHLLECAKELDVQIIGVKFHVSSACKESQVYV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Antizyme inhibitor 1 Antibody

Immunocytochemistry/ Immunofluorescence: Antizyme inhibitor 1 Antibody [NBP1-82497]

Immunocytochemistry/ Immunofluorescence: Antizyme inhibitor 1 Antibody [NBP1-82497]

Immunocytochemistry/Immunofluorescence: Antizyme inhibitor 1 Antibody [NBP1-82497] - Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: Antizyme inhibitor 1 Antibody [NBP1-82497]

Immunohistochemistry-Paraffin: Antizyme inhibitor 1 Antibody [NBP1-82497]

Immunohistochemistry-Paraffin: Antizyme inhibitor 1 Antibody [NBP1-82497] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes.

Applications for Antizyme inhibitor 1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF,Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Antizyme inhibitor 1

Antizyme inhibitor 1, or AZIN1 for short, consists of a 448 amino acid isoform that is 49 kDa, and is involved in the stabilization of ornithine decarboxylase antizymes, which help to regulate polyamine biosynthesis and homeostasis. Disease research is currently being conducted with AZIN1 and a variety of diseases and disorders to determine the relationship between the two. These diseases include Fanconi's anemia, malaria, liver cirrhosis, prostatitis, Hepatitis C, Hepatitis B, fibrosis, anemia, and prostate cancer. This protein interacts with OAZ2, FANCA, FANCC, OAZ1, and OAZ3 in processes linked to metabolism and regulation of catalytic activity.

Alternate Names

antizyme inhibitor 1, AZI, OAZIMGC691, OAZINEC 4.1.1.17, ODC1L, Ornithine decarboxylase antizyme inhibitorMGC3832

Entrez Gene IDs

51582 (Human)

Gene Symbol

AZIN1

UniProt

O14977 (Human)

Additional Antizyme inhibitor 1 Products

Product Documents for Antizyme inhibitor 1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Antizyme inhibitor 1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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