Apc1 [p Ser377] Antibody

Biological Validation

Unconjugated

Polyclonal Rabbit IgG

Please see the vial label for concentration. If unlisted please contact technical services.

This affinity purified Apc1 [p Ser377] Antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region surrounding pS377 of Human Apc1 protein. (Uniprot: Q9H1A4)

A BLAST analysis was used to suggest reactivity with this protein from human, dog, rat, and bovine based on 100% homology for the immunogen sequence. Cross reactivity with Apc1 protein from mouse is expected, as this sequence show 90% homologous between human and mouse. Cross reactivity with Apc1 homologues from other sources has not been determined. Minimal reactivity is expected with the non-phosphorylated form of the protein.

p Ser377

Secreted

This product is an affinity purified antibody produced by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities. This antibody is specific for phosphorylated human Apc1 protein at the pS377 residue. A BLAST analysis was used to suggest reactivity with this protein from human, dog, rat, and bovine based on 100% homology for the immunogen sequence. Cross reactivity with Apc1 protein from mouse is expected, as this sequence show 90% homologous between human and mouse. Cross reactivity with Apc1 homologues from other sources has not been determined. Minimal reactivity is expected with the non-phosphorylated form of the protein.

Polyclonal

Rabbit

IgG

This product is an affinity purified antibody produced by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities

Store vial at -20C prior to opening. Aliquot contents and freeze at -20C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4C as an undiluted liquid. Dilute only prior to immediate use.

Immunogen affinity purified

0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

0.01% Sodium Azide

Please see the vial label for concentration. If unlisted please contact technical services.

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Store at -20C short term. Aliquot and store at -80C long term. Avoid freeze-thaw cycles.