Apc7 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77379

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all Apc7 Antibodies »

Product Specifications

Immunogen

Antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human APC7. The immunogen is located within amino acids 520 - 570 of APC7. Amino Acid Squence: LDPNDQKSLEGMQKMEME

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

68 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Apc7 Antibody - BSA Free

Western Blot: Apc7 AntibodyBSA Free [NBP1-77379]

Western Blot: Apc7 AntibodyBSA Free [NBP1-77379]

Western Blot: Apc7 Antibody [NBP1-77379] - Analysis in HeLa cell lysate with antibody at 1 ug/mL.
Immunocytochemistry/ Immunofluorescence: Apc7 Antibody - BSA Free [NBP1-77379]

Immunocytochemistry/ Immunofluorescence: Apc7 Antibody - BSA Free [NBP1-77379]

Immunocytochemistry/Immunofluorescence: Apc7 Antibody [NBP1-77379] - Rat kidney tissue with APC7 antibody at 20 ug/mL.

Applications for Apc7 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Apc7

Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC7 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC7 is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with various transcription coactivators.

Alternate Names

anaphase promoting complex subunit 7, anaphase-promoting complex subunit 7, APC7Cyclosome subunit 7

Gene Symbol

ANAPC7

UniProt

NP_057322 (Human)

Additional Apc7 Products

Product Documents for Apc7 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Apc7 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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