ApoE4 Antibody (4E4) [Janelia Fluor® 549]
Novus Biologicals, part of Bio-Techne | Catalog # NBP1-49529JF549
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Human
Applications
ELISA, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Western Blot
Label
Janelia Fluor 549
Antibody Source
Monoclonal Mouse IgG1 kappa Clone # 4E4
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Synthetic peptide made to an internal region of human ApoE4 (within residues 100-150)
Localization
Secreted
Specificity
This antibody is specific for ApoE4. It does not cross-react with the ApoE2 or ApoE3 isoforms.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1 kappa
Applications for ApoE4 Antibody (4E4) [Janelia Fluor® 549]
Application
Recommended Usage
ELISA
Optimal dilutions of this antibody should be experimentally determined.
Immunocytochemistry/ Immunofluorescence
Optimal dilutions of this antibody should be experimentally determined.
Immunoprecipitation
Optimal dilutions of this antibody should be experimentally determined.
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein G purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: ApoE4
Lipoproteins are responsible for carrying cholesterol and other fats through the bloodstream as little packages and are essential for the normal breakdown of these molecules. In particular, apolipoprotein E is a major component of very low-density lipoproteins (VLDL), which remove excess cholesterol from the blood and carry it to the liver for processing. Maintaining normal levels of cholesterol is essential for the prevention of cardiovascular diseases, including heart attacks and strokes.
There are three known Apo E isoforms (ApoE2, E3 and E4), which are strongly associated with cardiovascular disease and/orAlzheimer's disease. Therefore, ApoE antibodies have become useful tools for research in both of these areas.
Alternate Names
Apo-E, apolipoprotein E, apolipoprotein E3, late onset), MGC1571
Gene Symbol
APOE
Additional ApoE4 Products
Product Documents for ApoE4 Antibody (4E4) [Janelia Fluor® 549]
Product Specific Notices for ApoE4 Antibody (4E4) [Janelia Fluor® 549]
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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