APPBP1 Antibody (4E8-H3)

Novus Biologicals, part of Bio-Techne | Catalog # H00008883-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 4E8-H3

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all APPBP1 Antibodies »

Product Specifications

Immunogen

APPBP1 (AAH00480, 1 a.a. ~ 534 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

MAQLGKLLKEQKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFFLQRSSIGKNRAEAAMEFLQELNSDVSGSFVEESPENLLDNDPSFFCRFTVVVATQLPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIIIKEHPVIESHPDNALEDLRLDKPFPELREHFQSYDLDHMEKKDHSHTPWIVIIAKYLAQWYSETNGRIPKTYKEKEDFRDLIRQGILKNENGAPEDEENFEEAIKNVNTALNTTQIPSSIEDIFNDDRCINITKQTPSFWILARALKEFVAKEGQGNLPVRGTIPDMIADSGKYIKLQNVYREKAKKDAAAVGNHVAKLLQSIGQAPESISEKELKLLCSNSAFLRVVRCRSLAEEYGLDTINKDEIISSMDNPDNEIVLYLMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMVKDDYVHEFCRYGAAEPHTIAAFLGGAAAQEVIKIITKQFVIFNNTYIYSGMSQTSATFQL

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for APPBP1 Antibody (4E8-H3)

Western Blot: APPBP1 Antibody (4E8-H3) [H00008883-M01]

Western Blot: APPBP1 Antibody (4E8-H3) [H00008883-M01]

Western Blot: NEDD8 Activating Enzyme (APPBP1/UBA3) Antibody (4E8-H3) [H00008883-M01] - APPBP1 monoclonal antibody (M01), clone 4E8-H3 Analysis of APPBP1 expression in HeLa.
Western Blot: APPBP1 Antibody (4E8-H3) [H00008883-M01]

Western Blot: APPBP1 Antibody (4E8-H3) [H00008883-M01]

Western Blot: NEDD8 Activating Enzyme (APPBP1/UBA3) Antibody (4E8-H3) [H00008883-M01] - APPBP1 monoclonal antibody (M01), clone 4E8-H3. Analysis of APPBP1 expression in A-431.
Sandwich ELISA: NEDD8 Activating Enzyme (APPBP1/UBA3) Antibody (4E8-H3) [H00008883-M01] - Detection limit for recombinant GST tagged APPBP1 is approximately 0.3ng/ml as a capture antibody.

Applications for APPBP1 Antibody (4E8-H3)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Sandwich ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: APPBP1

The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.

Long Name

Amyloid beta Precursor Protein-binding Protein 1

Alternate Names

NAE1

Entrez Gene IDs

8883 (Human)

Gene Symbol

NAE1

OMIM

603385 (Human)

UniProt

AAH00480 (Human)

Additional APPBP1 Products

Product Documents for APPBP1 Antibody (4E8-H3)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for APPBP1 Antibody (4E8-H3)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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