Aprataxin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-39041

Novus Biologicals, part of Bio-Techne
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NBP2-39041
NBP2-39041-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Aprataxin Antibodies »

Product Summary for Aprataxin Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: HMVNELYPYIVEFEEEAKNPGLETHRKRKRSGNSDSIERDAAQEAEAGTGLEPGSNSGQCSVPLKKGKDAPIKKESLGHWSQGLKISMQDPKMQVYKD

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Aprataxin Antibody

Immunocytochemistry/ Immunofluorescence: Aprataxin Antibody [NBP2-39041]

Immunocytochemistry/ Immunofluorescence: Aprataxin Antibody [NBP2-39041]

Immunocytochemistry/Immunofluorescence: Aprataxin Antibody [NBP2-39041] - Immunofluorescent staining of human cell line PC-3 shows localization to nucleus & nucleoli.
Immunohistochemistry: Aprataxin Antibody [NBP2-39041]

Immunohistochemistry: Aprataxin Antibody [NBP2-39041]

Immunohistochemistry: Aprataxin Antibody [NBP2-39041] - Staining of human cerebral cortex shows strong nuclear positivity in neuronal cells.

Applications for Aprataxin Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Aprataxin

Aprataxin encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.

Alternate Names

AOA1EAOH, AOAMGC1072, aprataxin, ataxia 1, early onset with hypoalbuminemia, AXA1, EC 3.-, EOAHA, FHA-HIT, FLJ20157, Forkhead-associated domain histidine triad-like protein

Gene Symbol

APTX

UniProt

Q7Z2E3 (Human)

Additional Aprataxin Products

Product Documents for Aprataxin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Aprataxin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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