Aquaporin-5 Antibody (SR1459)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21684

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21684-100ul
NBP3-21684-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1459

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Aquaporin 5/AQP5 Antibodies »

Product Summary for Aquaporin-5 Antibody (SR1459)

Immunogen

A synthesized peptide derived from human Aquaporin-5 (Uniprot #: P55064)

Specificity

Detects endogenous levels of Aquaporin-5

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

28 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Aquaporin-5 Antibody (SR1459)

Immunohistochemistry: Aquaporin-5 Antibody (SR1459) [NBP3-21684] -

Immunohistochemistry: Aquaporin-5 Antibody (SR1459) [NBP3-21684] - Immunohistochemical analysis of paraffin-embedded mouse lung, using NBP3-21684.

Western Blot: Aquaporin-5 Antibody (SR1459) [NBP3-21684] -

Western Blot: Aquaporin-5 Antibody (SR1459) [NBP3-21684] - Western blot analysis using NBP3-21684 in SW480 cell lysate.

Applications for Aquaporin-5 Antibody (SR1459)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunohistochemistry

1:50-1:200

Western Blot

1:1000-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Aquaporin 5/AQP5

Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. At least ten isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP9. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7 and AQP9 are permeable to urea and glycerol. AQP2 is the only water channel that is activated by vasopressin to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation, and the secretion and reabsorption of cerebrospinal fluid and aqueous humor. In the lung, the 27-kDa AQP5 is responsible for the majority of water transport across the apical membrane of type I alveolar epithelial cells. The gene encoding human AQP5 maps to chromosome 12q13.

Long Name

Aquaporin 5

Alternate Names

AQP-5, AQP5, PPKB

Gene Symbol

AQP5

Additional Aquaporin 5/AQP5 Products

Product Documents for Aquaporin-5 Antibody (SR1459)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Aquaporin-5 Antibody (SR1459)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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