Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human, Mouse

Cited:

Mouse

Applications

Validated:

Immunoprecipitation, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all ARAP1 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 1160 and 1210 of human centaurin, delta 2 (ankyrin repeat, and pleckstrin homology domains-containing protein 1) using the numbering given in entry NP_056057.1 (GeneID 116985).

Reactivity Notes

Mouse reactivity reported in (PMID: 22573888).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ARAP1 Antibody

Western Blot: ARAP1 Antibody [NB100-68223]

Western Blot: ARAP1 Antibody [NB100-68223]

Western Blot: ARAP1 Antibody [NB100-68223] - Detection of Human CENTD2/ARAP1 on HeLa whole cell lysate using NB100-68223. CENTD2/ARAP1 was also immunoprecipitated by another rabbit anti-CENTD2/ARAP1 antibody.

Applications for ARAP1 Antibody

Application
Recommended Usage

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000
Application Notes
WB reactivity reported in (PMID: 22573888).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: ARAP1

The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. The RHO-GAP activity may mediate cell rounding and loss of stress fibers. At least three transcript variants encoding different isoforms have been found for this gene, but the full-length natures of all variants have not been determined.

Alternate Names

arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1, ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1, centaurin, delta 2, Centaurin-delta-2, CENTD2ARF-GAP, RHO-GAP, ankyrin repeat, and pleckstrin homology domains-containingprotein 1, Cnt-d2, KIAA0782centaurin-delta-2

Entrez Gene IDs

116985 (Human)

Gene Symbol

ARAP1

UniProt

Q96P48 (Human)

Additional ARAP1 Products

Product Documents for ARAP1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for ARAP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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