ARFIP2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-33195

Novus Biologicals, part of Bio-Techne
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NBP1-33195
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (98%), Mouse (99%), Rat (99%), Sheep (98%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ARFIP2 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human ARFIP2. The exact sequence is proprietary.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

38 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ARFIP2 Antibody

Western Blot: ARFIP2 Antibody [NBP1-33195]

Western Blot: ARFIP2 Antibody [NBP1-33195]

Western Blot: ARFIP2 Antibody [NBP1-33195] - Sample (30 ug of whole cell lysate) A: Molt-4 10% SDS PAGE; antibody diluted at 1:10000.
Immunohistochemistry-Paraffin: ARFIP2 Antibody [NBP1-33195]

Immunohistochemistry-Paraffin: ARFIP2 Antibody [NBP1-33195]

Immunohistochemistry-Paraffin: ARFIP2 Antibody [NBP1-33195] - Paraffin-embedded human cervical cancer. ARFIP2 antibody [N1C2] diluted at 1:500.
Immunohistochemistry-Paraffin: ARFIP2 Antibody [NBP1-33195]

Immunohistochemistry-Paraffin: ARFIP2 Antibody [NBP1-33195]

Immunohistochemistry-Paraffin: ARFIP2 Antibody [NBP1-33195] - Paraffin-embedded human endometrial cancer. ARFIP2 antibody [N1C2] diluted at 1:500.

Applications for ARFIP2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:5000-1:20000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: ARFIP2

ARFIP2 is a ubiquitously expressed protein implicated in mediating cross talk between RAC and ARF small GTPases. It has been shown that ARFIP2 binds specifically to GTP-bound ARF1 and ARF6, but binds to Rac-GTP and Rac-GDP with similar affinities. The X-ray structure of arfaptin reveals an elongated, crescent-shaped dimer of 3-helix coiled-coils. Structures of arfaptin with Rac bound to either GDP or the slowly hydrolysable analog GMPPNP show that the switch regions adopt similar conformations in both complexes.

Alternate Names

ADP-ribosylation factor interacting protein 2, ADP-ribosylation factor-interacting protein 2, arfaptin 2, arfaptin-2, Partner of RAC1, POR1partner of RAC1 (arfaptin 2), Protein POR1

Gene Symbol

ARFIP2

Additional ARFIP2 Products

Product Documents for ARFIP2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for ARFIP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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