ARG2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-15445

Novus Biologicals, part of Bio-Techne
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NBP2-15445
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (94%), Rhesus Macaque (98%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Arginase 2/ARG2 Antibodies »

Product Summary for ARG2 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human ARG2. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Dog (83%), Rabbit (88%), Chicken (81%).

Localization

Mitochondrion

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

39 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ARG2 Antibody

Western Blot: ARG2 Antibody [NBP2-15445]

Western Blot: ARG2 Antibody [NBP2-15445]

Western Blot: ARG2 Antibody [NBP2-15445] - Non-transfected (-) and transfected (+) 293T whole cell extracts (50 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with ARG2 antibody diluted at 1:2000. HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
Immunocytochemistry/ Immunofluorescence: ARG2 Antibody [NBP2-15445]

Immunocytochemistry/ Immunofluorescence: ARG2 Antibody [NBP2-15445]

Immunocytochemistry/Immunofluorescence: ARG2 Antibody [NBP2-15445] - HepG2 cells were fixed in ice-cold MeOH for 5 min. Green: ARG2 protein stained by ARG2 antibody diluted at 1:500. Blue: Hoechst 33342 staining.
Immunohistochemistry-Paraffin: ARG2 Antibody [NBP2-15445]

Immunohistochemistry-Paraffin: ARG2 Antibody [NBP2-15445]

Immunohistochemistry-Paraffin: ARG2 Antibody [NBP2-15445] - Paraffin-embedded mouse kidney. ARG2 antibody dilution: 1:500.
View 3 more images

Applications for ARG2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Arginase 2/ARG2

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. [provided by RefSeq]

Long Name

Kidney-Type Arginase

Alternate Names

ARG2, Arginase-2, Type II Arginase

Gene Symbol

ARG2

UniProt

P78540

Additional Arginase 2/ARG2 Products

Product Documents for ARG2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for ARG2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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