ARHGEF7 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-12453

Novus Biologicals, part of Bio-Techne
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NBP3-12453
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

ELISA, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ARHGEF7 Antibodies »

Product Summary for ARHGEF7 Antibody

Immunogen

Synthetic peptide taken within amino acid region 595-805 on human ARHGEF7 protein.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for ARHGEF7 Antibody

Western Blot: ARHGEF7 Antibody [NBP3-12453]

Western Blot: ARHGEF7 Antibody [NBP3-12453]

Western Blot: ARHGEF7 Antibody [NBP3-12453] - MDA cells, 1:500 antibody dilution in DiluObuffer. Apparent MW is 85 KDa.

Applications for ARHGEF7 Antibody

Application
Recommended Usage

ELISA

1:10000

Immunoprecipitation

1:200

Western Blot

1:500
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary).

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.

Background: ARHGEF7

ARHGEF7, also known as Rho guanine nucleotide exchange factor 7, contains many isoforms that are 90 kDa, 87 kDa, 84 kDa, 82 kDa, 73 kDa, and 70 kDa, and is involved in apoptosis regulation, cell migration, and cell spreading. Current disease research is being conducted on ARHGEF7 and its relation to Borjeson-Forssmann-Lehmann Syndrome, t-cell leukemia, breast cancer, Wiskott-Aldrich Syndrome, insulin resistance, neuronitis, pancreatitis, leukemia, neuroblastoma, insulin resistance, adenocarcinoma, and lung cancer. This protein is linked to the GPCR pathway and the RhoA pathway, and it interacts with SCRIB, CBL, GIT1, PAK1, and CBLB.

Alternate Names

Beta-Pix, COOL1COOL-1, DKFZp686C12170, DKFZp761K1021, guanine nucleotide exchange factor 7, KIAA0142KIAA0412, Nbla10314, P50, P50BP, p85, P85COOL1, P85SPRBETA-PIX, PAK3, PAK3BP, PIXBPAK-interacting exchange factor beta, Rho guanine nucleotide exchange factor (GEF) 7, rho guanine nucleotide exchange factor 7, SH3 domain-containing proline-rich protein

Gene Symbol

ARHGEF7

Additional ARHGEF7 Products

Product Documents for ARHGEF7 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ARHGEF7 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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