ARMC8 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-55188

Novus Biologicals, part of Bio-Techne
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NBP2-55188
NBP2-55188-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (97%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ARMC8 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: LEGEHNIEVKEQTLCILANIADGTTAKDLIMTNDDILQKIKYYMGHSHVKLQLAAMFCISNLIWNEEEGSQERQDKLRDMGIVDILHKLSQSPDSNL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ARMC8 Antibody

Immunocytochemistry/ Immunofluorescence: ARMC8 Antibody [NBP2-55188]

Immunocytochemistry/ Immunofluorescence: ARMC8 Antibody [NBP2-55188]

Immunocytochemistry/Immunofluorescence: ARMC8 Antibody [NBP2-55188] - Staining of human cell line A-431 shows localization to nucleoplasm & vesicles.

Applications for ARMC8 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ARMC8

ARMC8 (armadillo-repeat-containing protein 8) is part of the conserved CTLH protein complex, where it is present as two alternatively spliced forms: ARMC8alpha and ARMC8beta. Studies have indicated that ARMC8alpha promotes protein degradation by both the proteasome-dependent and the vacuole/lysosome-dependent pathways, by interacting directly with the protein to be degraded or by associating with the monoubiquitin-binding protein HRS respectively. (The CTLH complex is also surmised to be involved in microtubule dynamics.)

Alternate Names

armadillo repeat containing 8, armadillo repeat-containing protein 8, DKFZP434A043, HSPC056, MGC10058, MGC4880

Gene Symbol

ARMC8

Additional ARMC8 Products

Product Documents for ARMC8 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ARMC8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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