ASAP1 Antibody

Immunohistochemistry: ASAP1 Antibody [NBP2-48909] -

Immunohistochemistry: ASAP1 Antibody [NBP2-48909] - Loss of ASAP1 results in expansion of the hypertrophic zone.(A-D) E15.5 Asap1+/+ & Asap1GT/GT growth plates of the humerus stained for Alcian Blue / von Kossa in blue & black, respectively. The length of the hypertrophic zone (hz) is demarcated by a black bar. (E-T) Immunostaining of E15.5 Asap1+/+ & Asap1GT/GT humeral growth plates. Staining of the hypertrophic marker collagen X (E-H) & the osteogenic markers osteocalcin (I-L) & osteopontin (M-P) was detected by Nova Red & counterstained with hematoxilin. ASAP1 immunostaining indicates specific expression of ASAP1 in the perichondrium, in late hypertrophic chondrocytes & in the primary ossification center (Q-T). The scale bars shown at the bottom of the panels apply to all pictures above the given scale bar. (U) Quantification of the distal hypertrophic zones of the humerus of Asap1+/+ & Asap1GT/GT animals (Asap1+/+ n = 5, Asap1GT/GT n = 5). Graphs show the mean ± SD. Significance was calculated using the Student’s t-test. **, p <0.005. Image collected & cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/31246957), licensed under a CC-BY license. Not internally tested by Novus Biologicals.