Asparagine synthetase Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87444

Novus Biologicals, part of Bio-Techne
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NBP1-87444
NBP1-87444-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Mouse (94%), Rat (93%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Asparagine Synthetase/ASNS Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: QHFEFEYQTKVDGEIILHLYDKGGIEQTICMLDGVFAFVLLDTANKKVFLGRDTYGVRPLFKAMTEDGFLAVCSEAKGLVTLKHSATPFLKVEPFLPGHYEVLDLKPNGKVASVEMVKYHHCRDVP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Asparagine synthetase Antibody

Western Blot: Asparagine synthetase Antibody [NBP1-87444]

Western Blot: Asparagine synthetase Antibody [NBP1-87444]

Western Blot: Asparagine synthetase Antibody [NBP1-87444] - Analysis in human cell line SK-MEL-30.
Immunohistochemistry-Paraffin: Asparagine synthetase Antibody [NBP1-87444]

Immunohistochemistry-Paraffin: Asparagine synthetase Antibody [NBP1-87444]

Immunohistochemistry-Paraffin: Asparagine synthetase Antibody [NBP1-87444] - Staining of human stomach shows moderate cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: Asparagine synthetase Antibody [NBP1-87444]

Immunohistochemistry-Paraffin: Asparagine synthetase Antibody [NBP1-87444]

Immunohistochemistry-Paraffin: Asparagine synthetase Antibody [NBP1-87444] - Staining of human cerebral cortex shows moderate cytoplasmic positivity in neurons.
View 2 more images

Applications for Asparagine synthetase Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
WB reported in scientific literature (PMID: 30244971). For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Asparagine Synthetase/ASNS

Asparagine synthetase (AS) is a housekeeping enzyme responsible for the production of asparagine from aspartate and glutamine. Most mammalian cells express AS and regulate the level of activity in response to the concentration of asparagine in the medium. Certain tumor cells in contrast, exhibit little or no AS activity and rely on the surrounding medium as a source of exogenous asparagines (1). Therefore tumor cells may be selectively killed by a chemotherapeutic drug using asparaginase. This approach has been exploited in the treatment of certain cancers like childhood acute lymphoblastic leukemia (2).

Long Name

ASNS

Alternate Names

ASNSD, EC 6.3.5.4, Glutamine Dependent Asparagine Synthetase, TS11 Cell Cycle Control Protein

Gene Symbol

ASNS

Additional Asparagine Synthetase/ASNS Products

Product Documents for Asparagine synthetase Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Asparagine synthetase Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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