ATF3 Antibody (S08-6H6)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-15001

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-15001-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S08-6H6

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ATF3 Antibodies »

Product Summary for ATF3 Antibody (S08-6H6)

Immunogen

Recombinant protein of human ATF3 (Uniprot#: P18847)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

21 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ATF3 Antibody (S08-6H6)

Western Blot: ATF3 Antibody (S08-6H6) [NBP3-15001]

Western Blot: ATF3 Antibody (S08-6H6) [NBP3-15001]

Western Blot: ATF3 Antibody (S08-6H6) [NBP3-15001] - Western blot detection of ATF3 in A549, MCF-7, U251, HL-60 cell lysates using ATF3 Rabbit mAb (1:1000 diluted). Predicted band size: 21kDa. Observed band size: 21kDa.

Applications for ATF3 Antibody (S08-6H6)

Application
Recommended Usage

Western Blot

1/1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ATF3

Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes.

Alternate Names

activating transcription factor 3cAMP-dependent transcription factor ATF-3, ATF3deltaZip2, ATF3deltaZip2c, ATF3deltaZip3, cyclic AMP-dependent transcription factor ATF-3

Gene Symbol

ATF3

Additional ATF3 Products

Product Documents for ATF3 Antibody (S08-6H6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ATF3 Antibody (S08-6H6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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